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Bio Excellence international Tech Co.,Ltd has been acting as sole agent for the sale of flexcell products for more than ten years,Bio Excellence can provide free technical guidance for flexcell tension, compression, fluid shear products, user site installation as well as training, until the user can use them without limiting number of training times.If you have any questions, please do not hesitate to contact us.
Flexcll tissue train 3D culture system
A computer-regulated bioreactor that allows users to create 3-dimensional cell-seeded gels and apply uniaxial tensile strains to these gels.
- Construct tethered, linear, 3-D cell-seeded collagen gels using a trough loader mold device and Flexcell® Tissue Train® culture plates with or without cyclic tension
- Apply a load regimen of uniaxial cyclic strain using a Flexcell® Tension System and Arctangle® loading posts
- Apply user-defined strain regimens to simulate heart rate, walking, running and other dynamic exercise patterns to tissue constructs
- Build bioartificial tissue samples of skin, tendon, ligament, etc. up to 35 mm in length
- Observe responses of cells cultured in 3-D matrices with phase contrast, fluorescent, or scanning confocal microscopy
- Tissue Train® Culture System is compatible with Windows 10.
flexcell Tissue Train® 3D Culture System is a computer-regulated cell stretching bioreactor system that allows users to create 3-dimensional cell-seeded gels and apply uniaxial or equibiaxial tensile strains to these gels. The Tissue Train® 3D Culture System is a uniaxial system that allows researchers to apply user-defined strain regimens to simulate heart rate, walking, running, and other dynamic exercise patterns to tissue constructs. This will enable you to build bioartificial tissue samples of skin, tendon, ligament, etc. up to 35 mm in length.
Circular Foam Tissue Train® Culture Plate>>More
Create circular 3D cell-seeded gel constructs, while applying a load regimen of equibiaxial cyclic strain using the Flexcell® FX-6000™ Tension System.
- Matrix bonded foam anchors for improved cell attachment
- Monitor changes in cell shape, tissue organziation, cell migration, division, gene expression, protein secretion and expression
- Covalently bonded matrix: Untreated, Amino, Collagen (Type I, IV), Elastin, Pronectin (RGD), and Laminin (YISGR)
Cat No Description
TTCF-4001U Circular Foam Culture Plate --Untreated
TTCF-4001A Circular Foam Culture Plate --Amino
TTCF-4001C Circular Foam Culture Plate --Collagen Type I
TTCF-4001C(IV) Circular Foam Culture Plate --Collagen Type IV
TTCF-4001E Circular Foam Culture Plate --Elastin
TTCF-4001P Circular Foam Culture Plate --ProNectin
TTCF-4001L Circular Foam Culture Plate --Laminin
- Available individually or in case quantity of 40 plates
A) Close-up of open cell foam Bar = 1 mm B) Top view of a well in a 6-well Tissue Train® Circular Foam Culture Plate C) Top view of a well with Collagel® matrix solution attached to the foam ring.
Flexcell® scanflex® with xyflex®
use to Measure gel compaction in 3-D bioartificial tissues
SCANflex® Automated Scanning Device
Automated repetitive scanning process.Scans and saves images of 3-D tissue constructs.
User defined frequency and time intervals of image capture.
Can be used with the Tissue Train system to determine the compaction kinetics (change in area) of 3-D cell seeded-gels.
Scans four 6-well Tissue train culture plates placed on the scanner bed.
Images can be imported into Xyflex® program to analyze area measurement.
XYflex® Area Measurement Software
Automated area measurement in a series of images.
Evaluates the area compaction of 3-D bioartificial tissue constructs.
Compatible with images captured with the Scanflex® system.
Creates Excel and Text files for evaluation of changes in area.
Plots compaction curves as gel culture area vs. time.
Linear Tissue Train® Culture Plate >>More
Works with the Tissue Train® System to create linear, tethered 3D cell-seeded gel constructs and to provide uniaxial cyclic strain to cells in a gel matrix.
- Apply a load regimen of uniaxial cyclic strain to the 3D cell-seeded gel using Artangle® loading stations and the Flexcell® Tissue Train® System
- Mix preferred cell type in 3D collagen gel using a novel Trough Loader mold device
- Available in matrix bonded cerex nylon mesh or urethane polyester foam anchor tabs for improved cell attachment
Cat No Description
TT-5001U Tissue Train Culture Plate --Untreated
TT-5001A Tissue Train Culture Plate --Amino
TT-5001C Tissue Train Culture Plate --Collagen Type I
TT-5001C(IV) Tissue Train Culture Plate --Collagen Type IV
TT-5001E Tissue Train Culture Plate --Elastin
TT-5001P Tissue Train Culture Plate --ProNectin
TT-5001L Tissue Train Culture Plate --Laminin
Cat No Description
TT-4001U Tissue Train Culture Plate --Untreated
TT-4001A Tissue Train Culture Plate --Amino
TT-4001C Tissue Train Culture Plate --Collagen Type I
TT-4001C(IV) Tissue Train Culture Plate --Collagen Type IV
TT-4001E Tissue Train Culture Plate --Elastin
TT-4001P Tissue Train Culture Plate --ProNectin
TT-4001L Tissue Train Culture Plate --Laminin
Works with the Linear Trough Loaders 6-well and Arctangle® Loading Stations 6-well:
Figure Linear Trough Loaders 6-well
Molds for creating various shaped 3D cellseeded gel constructs with the Tissue
Train® Culture System .
Comprised of a Lexan plate with 6 individual, removable posts.
Available in linear and trapezoidal shaped molds.
Available in a set of four or as part of a baseplate kit.
Figure Arctangle® Loading Stations 6-well
- Packaged individually or in case quantity of 40 plates
Trapezoidal Tissue Train® Culture Plate>>More
Works with the Tissue Train® System to create 3D trapezoidal-shaped bioartificial tissue constructs.
- Create 3D collagen gel constructs using a Trapezodial Trough Loader® as a mold device
- Apply a load regimen of uniaxial cyclic strain to the 3D cell-seeded gel using the Flexcell® Tissue Train® System
- Matrix bonded nylon mesh or foam anchors for improved cell attachment
- Available individually or case quantity of 40 plates
TTTP-4001U Trapezoidal TT Culture Plate --Untreated
TTTP-4001A Trapezoidal TT Culture Plate --Amino
TTTP-4001C Trapezoidal TT Culture Plate --Collagen Type I
TTTP-4001C(IV) Trapezoidal TT Culture Plate --Collagen Type IV
TTTP-4001E Trapezoidal TT Culture Plate --Elastin
TTTP-4001P Trapezoidal TT Culture Plate --ProNectin
TTTP-4001L Trapezoidal TT Culture Plate --Laminin
TTTP-5001U Trapezoidal TT Culture Plate --Untreated
TTTP-5001A Trapezoidal TT Culture Plate --Amino
TTTP-5001C Trapezoidal TT Culture Plate --Collagen Type I
TTTP-5001C(IV) Trapezoidal TT Culture Plate --Collagen Type IV
TTTP-5001E Trapezoidal TT Culture Plate --Elastin
TTTP-4001P Trapezoidal TT Culture Plate --ProNectin
TTTP-5001L Trapezoidal TT Culture Plate --Laminin
Collagel® and Thermacol® Kits>>More
Collagen gel solution with rapid gelation at 37 C (see Fig. 1 below).
- All components in one kit for creating a 3D cell-seeded bioartificial type I collagen gel (see Fig. 2 below).
- Multiple applications including tissue engineering, migration studies, differentiation, chemotaxis, cell interactions, & matrix interactions.
- Kit contains atelopeptide and telopetide-containing type I collagen, 5X MEM, fetal bovine serum, 1 M hepes, and 0.1 M NaOH.
- Available in three sizes: mini, midi*, and maxi*.
*10% Savings (based on price of purchasing same number of mini kits individually)
Applications of Thermacol®
- 3D Cell Culture - culture cells in Collagel® to create a 3D cell-seeded type I collagen hydrogel.
- Tissue Engineering - use Collagel® with a Tissue Train® culture plate to create bioartificial tissues.
- Mechanical Load - culture cells in 3D then apply mechanical load with the Flexcell® Tension or Compression System.
- Drug Discovery - culturing cells in a 3D environment better mimics in vivo conditions and thus provides a platform to study the effects of various pharmacological agents on cells in a more natural environment.
Speed of gelation of 3D cell-seeded constructs made with Collagel® and Thermacol®.
Bioartificial tissue development with Thermacol® and the Tissue Train® Culture System.
